Siena will take on Brown in the Liberty NCR D1 final next week after both teams won semifinals this week.
Siena played rivals Iona for the second time this season, coming away with a 28-14 victory.
Siena defeated Iona Wednesday night in a make-up of a game that was canceled due to lightning back in September.
Iona went into the game 3-1 with Siena at 4-0.
Siena's offense was firing and they ran out to a 41-21 lead at halftime.
The team teams each scored two tries in the second half to cap it off, but in the end Siena won in a big-scoring game 55-33.
In what is almost a microcosm of how the college landscape continues to change, Siena College will be moved from NCR's D1AA postseason to the higher-level D1 postseason pathway.
It was a day of dramatic games in the NCR finals, and the Small-College Challenge bracket was no exception.
Western Oregon took third over College of Charleston in a game that was back and forth. Both teams seemed maybe a little run down early, but the action picked up as they sensed a chance for a strong end to the fall.
Siena and Wayne State will meet in the final of the NCR small-college challenge cup after both won big on Friday.